Hepatic spheroids are three-dimensional (3D) cell culture models made up of liver cells, often derived from hepatocytes, hepatic stellate cells and liver NPC. These spheroids mimic the in vivo architecture and functionality of the liver more closely than traditional 2D cell cultures, offering a more accurate representation of cellular interactions, metabolic activity, and tissue organization.

Hepatic spheroids are commonly used in research to study liver biology, drug metabolism, liver diseases, toxicity testing, and regenerative medicine. They provide valuable insights into hepatocyte behavior, cellular differentiation, and liver-specific functions like albumin secretion, urea synthesis, and detoxification processes. Additionally, hepatic spheroids are increasingly employed in personalized medicine and preclinical drug testing, providing a more reliable platform for evaluating the safety and efficacy of pharmaceutical compounds.

TDC-T1101-product-datasheet-Hepatic-Spheriod.pdf